You can access novel mental health and CNS treatments including psychedelic therapy by participating in clinical trials.
By participating, you not only help yourself but contribute to research that could impact millions.
Current Trials
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Investigational Medicinal Product: BPL-003 (5-MeO-DMT)
Phase: 2a
Indication: Alcohol Use Disorder
This study is looking for patients who have the following:
Aged between 18-64 years old
Min. of 4 heavy drinking days in the 28 days before screening
No more than 14 days elapsed since the completion of detoxification
Please visit clinicaltrials.gov for further details on the study.
Sponsored by Beckley Psytech.
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Investigational Medicinal Product: Xanamem™
Phase: 2
Indication: Major Depressive Disorder and Cognitive Impairment
This study is looking for patients who have the following:
Aged between 18-75 years old
Current diagnosis of MDD
Self-reported cognitive dysfunction
Currently or previously treated with first- or second-line antidepressant
Please visit clinicaltrials.gov for further details on the study.
Sponsored by Actinogen.
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Investigational Medicinal Product: Methylone
Phase: 1b / 2a
Indication: Post-Traumatic Stress Disorder
This study is looking for patients who have the following:
Aged between 18-65 years old
Current diagnosis of moderate to severe PTSD
Failed at least one treatment for PTSD (either psychotherapy or pharmacological treatment)
Not currently on any active treatments
Please visit clinicaltrials.gov for further details on the study.
Sponsored by Transcend Therapeutics.
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Investigational Medicinal Product: BPL-003
Phase: 2a
Indication: Treatment-Resistant Depression
This study is looking for patients who have the following:
Aged between 18 and 75 years old
Current diagnosis of at least moderate major depressive disorder (MDD)
Previously failed to respond to at least 2 pharmacological treatments
If currently taking antidepressant medications, willing and able to discontinue
Please visit clinicaltrials.gov for further details on the study.
Sponsored by Beckley Psytech.
Can’t find what you’re looking for?
How to join a trial?
1. Sign up to our platform
Complete a 2-min form to let us know which mental health or CNS conditions you might be struggling with.
2. Check your inbox periodically
If you’re potentially eligible for an existing or an upcoming trial, you’ll receive a more detailed questionnaire on your health.
3. Fill a detailed questionnaire
Your responses will allow us to identify your eligibility for a health screening on the phone. If you don’t hear from us, keep an eye on your inbox for other opportunities!
4. Speak to our team on the phone
You’ll have the chance to ask any questions about the specific trial while we get to know you better. If both sides are happy, you’ll be invited for a health check at our clinic.
5. Come to our clinic for screening
Our clinical team will carry out health checks, including blood tests and diagnostic questionnaires, to decide whether you can safely participate in the trial.
6. Enrol in a clinical trial
Once our team is satisfied with your health and safety, you’ll be enrolled in the trial. They’ll ensure you receive all the information and care you need. If you’re not eligible for a specific trial for any reason, we’ll still consider you for future trials.
Why participate?
Contribute to medical research
By taking part in a clinical trial, you can contribute to medical research and help advance knowledge about a particular condition or treatment, which could improve the lives of many.
Access to emerging treatments
You can get access to new and experimental treatments that are not yet available. While there is no guarantee that the treatment will work for you, you may be one of the first people to benefit.
Receive high quality care
Clinical trials are free to participate and cover all your expenses while providing you with high-quality care. Our clinical team are subject experts with a specialism in psychedelics and always prioritise your wellbeing.
How do psychedelic trials work?
1. Screening
Before taking part in a clinical trial, in order to minimise the risk of side effects, we will ask you to attend a medical checkup with our experienced doctors and nurses to make sure you meet the health criteria to take part.
2. Preparation
To prepare you emotionally and mentally for the experience, our trained therapists will discuss the therapy process with you and talk to you about your expectations and any concerns you may have.
3. Dosing
You’ll be given the psychedelic drug (or a placebo) in a comfortable room where your physical and psychological reactions can be monitored for safety. The therapist(s) will be available to provide you with emotional support and guidance throughout the experience.
4. Integration
Our therapists will work with you to interpret the psychedelic experience and discuss any insights or emotions that arose during the experience. They will help you identify thoughts or ideas that might lead to meaningful long-term change.
5. Follow-up
You will have check-ins with healthcare professionals to evaluate your long-term response to the treatment.
6. Discharge
Once your last check-in is complete, you will be discharged and provided with a summary of the trial results and any recommendations for further care.
FAQs
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Psychedelic drugs are a class of psychoactive substances that alter a person's perception, thoughts, and feelings. Examples of psychedelics include LSD, psilocybin (found in magic mushrooms), and DMT, which we study in our trials to treat conditions such as depression, post-traumatic stress disorder (PTSD) or adjustment disorder.
Psychedelic clinical trials are research studies that investigate the safety and effectiveness of psychedelic substances as a treatment for various mental health conditions. These trials are conducted in a controlled, clinical setting under the guidance of trained healthcare professionals on either healthy volunteers or patients. -
Researchers call the entry conditions for trials 'eligibility criteria'. Trials have these to make sure that the patients taking part in a trial are as similar as possible. That way, if one group does better than the other, researchers can be sure it was due to a difference in treatment and not due to their condition being more or less severe.
Eligibility criteria are clearly written in trial protocols. Examples where there are clear guidelines around eligibility could be age or the types of medication you are on or the diagnosis that you have. Eligibility criteria change for all trials so while you may not be eligible for one trial you may be for another.
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Our team will notify you if you meet the eligibility criteria for a trial based on the information you give us. That means it's important to keep your details up to date on the registration platform.
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If you subscribe to our mailing list above we will notify you when we have a new trial.
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You can register for our upcoming trials by filling out this form.
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Most clinical trials take place in major cities in the UK.
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We do not focus on a specific condition and carry out clinical trials for any condition our clients are interested in studying. This includes mental health conditions as well as CNS disorders.
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We do not focus on a specific drug and carry out clinical trials for any psychedelic drug our clients are interested in studying. This includes psilocybin, LSD, MDMA, and 5-MeO-DMT among others.
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All of our clinical trials are different so your involvement will vary depending on which trial you take part in. Some trials may involve multiple visits over a long period (in excess of 1 year) and on rare occasions may also require an overnight stay at one of our clinical facilities. Most of the trials we run at Clerkenwell Health will require you to attend a series of therapy sessions alongside a day or two of drug dosing over the course of 2 - 3 months. You will be made fully aware of what taking part will involve before you decide to take part in any of our studies.
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You may receive financial compensation for your time and be reimbursed for travel expenses if you take part in a clinical trial.
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When you take part in a clinical trial, it is important that you continue to take all the medications that are advised by your healthcare provider. Certain medications cannot be taken at the same time as the treatments we are testing in our trials and may affect whether you can take part. In some cases, you may still be able to take part but this will be discussed fully with you as part of our screening process.
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If you take part in a psychedelic-assisted psychotherapy trial you will be offered therapy and a psychedelic or a dummy drug. Therapy on its own can be helpful. Psychedelics have the potential to make therapy work better, but we don’t know for sure yet.