Find hope in breakthrough treatments through our clinical trials.
Your journey will be supported by caring specialists who see you as a person, not a participant – helping you access cutting-edge treatments, while supporting important research.
Current Trials
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Investigational Medicinal Product: MM120
Phase: 3
Indication: Generalized Anxiety Disorder
This study is looking for patients who have the following:
18 and 74 years of age
Meets DSM-5 criteria for generalized anxiety disorder
Free from any other clinically significant illness or disease
Please visit for clinicaltrials.gov further details on the study.
Sponsored by https://mindmed.co/
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Investigational Medicinal Product: COMP_006
Phase: 3
Indication: Treatment-Resistant Depression
This study is looking for patients who have the following:
Aged ≥18 years at Screening
Current diagnosis of at least moderate major depressive disorder (MDD)
Previously failed to respond to at least 2 pharmacological treatments
If currently taking antidepressant medications, willing and able to discontinue
Please visit clinicaltrials.gov for further details on the study.
Sponsored by https://compasspathways.com
Can’t find what you’re looking for?
How to join a trial?
1. Sign up to our platform
Complete a 2-min form to let us know which mental health or CNS conditions you might be struggling with.
2. Check your inbox periodically
If you’re potentially eligible for an existing or an upcoming trial, you’ll receive a more detailed questionnaire on your health.
3. Fill a detailed questionnaire
Your responses will allow us to identify your eligibility for a health screening on the phone. If you don’t hear from us, keep an eye on your inbox for other opportunities!
4. Speak to our team on the phone
You’ll have the chance to ask any questions about the specific trial while we get to know you better. If both sides are happy, you’ll be invited for a health check at our clinic.
5. Come to our clinic for screening
Our clinical team will carry out health checks, including blood tests and diagnostic questionnaires, to decide whether you can safely participate in the trial.
6. Enrol in a clinical trial
Once our team is satisfied with your health and safety, you’ll be enrolled in the trial. They’ll ensure you receive all the information and care you need. If you’re not eligible for a specific trial for any reason, we’ll still consider you for future trials.
Why participate?
Help transform healthcare
By taking part, you're not just accessing potential treatment – you're helping to prove that breakthrough therapies work, bringing hope to millions who will follow in your footsteps. Every person who participates helps bridge the gap between cutting-edge science and the people who need it most.
Access to breakthrough treatments
If conventional treatments haven't worked for you, a clinical trial could offer genuine hope. You'll receive innovative care from experienced doctors and psychiatrists in facilities designed specifically for your comfort and dignity. While we can't guarantee results, this could be your opportunity to access treatments that aren't yet available elsewhere – and help others facing similar struggles.
Experience care like no other
Clinical trials are free to participate in and cover all your expenses while providing exceptional, human-centered care. Our clinical team are central nervous system (CNS) specialists with deep expertise in psychedelics and mental health – and we actively hire staff who understand that vulnerability should be met with dignity and support.
How do psychedelic clinical trials work?
1. Screening
Before taking part in a clinical trial, in order to minimise the risk of side effects, we will ask you to attend a medical checkup with our experienced doctors and nurses to make sure you meet the health criteria to take part.
2. Preparation
To prepare you emotionally and mentally for the experience, our trained therapists will discuss the therapy process with you and talk to you about your expectations and any concerns you may have.
3. Dosing
You’ll be given the psychedelic drug (or a placebo) in a comfortable room where your physical and psychological reactions can be monitored for safety. The therapist(s) will be available to provide you with emotional support and guidance throughout the experience.
4. Integration
Our therapists will work with you to interpret the psychedelic experience and discuss any insights or emotions that arose during the experience. They will help you identify thoughts or ideas that might lead to meaningful long-term change.
5. Follow-up
You will have check-ins with healthcare professionals to evaluate your long-term response to the treatment.
6. Discharge
Once your last check-in is complete, you will be discharged and provided with a summary of the trial results and any recommendations for further care.
FAQs
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Psychedelic drugs are a class of psychoactive substances that alter a person's perception, thoughts, and feelings. Examples of psychedelics include LSD, psilocybin (found in magic mushrooms), and DMT, which we study in our trials to treat conditions such as depression, post-traumatic stress disorder (PTSD) or adjustment disorder.
Psychedelic clinical trials are research studies that investigate the safety and effectiveness of psychedelic substances as a treatment for various mental health conditions. These trials are conducted in a controlled, clinical setting under the guidance of trained healthcare professionals on either healthy volunteers or patients. -
Researchers call the entry conditions for trials 'eligibility criteria'. Trials have these to make sure that the patients taking part in a trial are as similar as possible. That way, if one group does better than the other, researchers can be sure it was due to a difference in treatment and not due to their condition being more or less severe.
Eligibility criteria are clearly written in trial protocols. Examples where there are clear guidelines around eligibility could be age or the types of medication you are on or the diagnosis that you have. Eligibility criteria change for all trials so while you may not be eligible for one trial you may be for another.
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Our team will notify you if you meet the eligibility criteria for a trial based on the information you give us. That means it's important to keep your details up to date on the registration platform.
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If you subscribe to our mailing list above we will notify you when we have a new trial.
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You can register for our upcoming trials by filling out this form.
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Most clinical trials take place in major cities in the UK.
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We do not focus on a specific condition and carry out clinical trials for any condition our clients are interested in studying. This includes mental health conditions as well as CNS disorders.
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We do not focus on a specific drug and carry out clinical trials for any psychedelic drug our clients are interested in studying. This includes psilocybin, LSD, MDMA, and 5-MeO-DMT among others.
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All of our clinical trials are different so your involvement will vary depending on which trial you take part in. Some trials may involve multiple visits over a long period (in excess of 1 year) and on rare occasions may also require an overnight stay at one of our clinical facilities. Most of the trials we run at Clerkenwell Health will require you to attend a series of therapy sessions alongside a day or two of drug dosing over the course of 2 - 3 months. You will be made fully aware of what taking part will involve before you decide to take part in any of our studies.
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You may receive financial compensation for your time and be reimbursed for travel expenses if you take part in a clinical trial.
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When you take part in a clinical trial, it is important that you continue to take all the medications that are advised by your healthcare provider. Certain medications cannot be taken at the same time as the treatments we are testing in our trials and may affect whether you can take part. In some cases, you may still be able to take part but this will be discussed fully with you as part of our screening process.
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If you take part in a psychedelic-assisted psychotherapy trial you will be offered therapy and a psychedelic or a dummy drug. Therapy on its own can be helpful. Psychedelics have the potential to make therapy work better, but we don’t know for sure yet.