Struggling with your mental health?

If existing options haven’t worked, you could access next-generation therapies through our clinical trials - safely, compassionately and at no cost to you.

Check your eligibility

Completely confidential. You can withdraw anytime.

  • " The entire team have been so welcoming, informative, attentive and kind throughout both trials. I've felt very safe and supported and able to freely share any queries or concerns. I feel fortunate to have had such a warm, structured and safe environment to journey through my own mind and learn how to better love, honour and accept myself. "

    Participant testimonial, 2024

  • " I found all interactions with Clerkenwell Health to be very positive. I felt the preparation by the therapy team was really thorough with a high level of care. On the dosing day I felt extremely safe and in good hands and the after care from both the medical staff and my assigned therapist was excellent "

    Participant testimonial, 2024

  • " The diligence and consideration given by the whole team has been exceptional, the program has been put together very well and I hope that many others will get the opportunity. "

    Participant testimonial, 2025

  • " Very understanding and professional team, a lot of care has been given to accommodate patients dealing with depression. "

    Participant testimonial, 2024

Current Trials

All our trials follow Good Clinical Practice (GCP) and research ethics standards.

  • Investigational Medicinal Product: MM120 

    Phase: 3

    Indication: Generalized Anxiety Disorder

    This study is looking for patients who have the following:

    • 18 and 74 years of age

    • Meets DSM-5 criteria for generalized anxiety disorder

    • Free from any other clinically significant illness or disease

    Please visit for clinicaltrials.gov further details on the study.

    Sponsored by https://mindmed.co/

    SIGN UP HERE →

  • Investigational Medicinal Product: COMP_006

    Phase: 3

    Indication: Treatment-Resistant Depression

    This study is looking for patients who have the following:

    • Aged ≥18 years at Screening

    • Current diagnosis of at least moderate major depressive disorder (MDD)

    • Previously failed to respond to at least 2 pharmacological treatments

    • If currently taking antidepressant medications, willing and able to discontinue

    Please visit clinicaltrials.gov for further details on the study.

    Sponsored by https://compasspathways.com

    SIGN UP HERE →

Can’t find what you’re looking for?

Sign up for future trials

Stay in the loop - no obligation to participate.

Why join a clinical trial?

Access breakthrough care, and help others do the same.

A chance to help others - at no cost to you

Taking part in a clinical trial won’t cost you anything. All study-related expenses, tests, and treatments are provided free of charge — and your participation could help advance future healthcare for others.

Real hope when treatments haven’t worked

If you’ve tried existing medications or therapy without success, a clinical trial could offer genuine hope. While we can't guarantee results, this could be your opportunity to access treatments that aren't yet available elsewhere.

Care that puts people first

Our team includes psychiatrists, therapists, and nurses who treat you as a person, not a trial participant. We actively hire staff who understand that vulnerability should be met with dignity and support.

How it works

1. Sign up to our platform

Complete a 5-min form to let us know which conditions you might be struggling with. Your responses will allow us to identify your eligibility for a health screening on the phone. If you don’t hear from us, keep an eye on your inbox for other opportunities!

2. Speak to our team on the phone

You’ll have the chance to ask any questions about the specific trial while we get to know you better. If both sides are happy, you’ll be invited for a health check at our clinic.

3. Come to our clinic for screening

Our clinical team will carry out health checks, including blood tests and diagnostic questionnaires, to decide whether you can safely participate in the trial.

4. Enrol in a clinical trial

Once our team is satisfied with your health and safety, you’ll be enrolled in the trial. They’ll ensure you receive all the information and care you need. If you’re not eligible for a specific trial for any reason, we’ll still consider you for future trials.

Join hundreds of others helping shape the future of mental healthcare.

Count me in!

Common questions people ask before joining

  • All our studies follow strict UK regulatory guidelines. Every trial is reviewed by ethics committees and led by psychiatrists, therapists and nurses experienced in mental health care. You’ll be carefully screened, supported throughout and can stop at any time.

  • You can withdraw at any point - before, during or after the trial - with no questions asked. Your wellbeing comes first, always.

  • You’ll never pay to take part. In many cases, we cover travel and related expenses. Some trials offer modest compensation for your time.

  • When you take part in a clinical trial, it is important that you continue to take all the medications that are advised by your healthcare provider. Certain medications cannot be taken at the same time as the treatments we are testing in our trials and may affect whether you can take part. In some cases, you may still be able to take part but this will be discussed fully with you as part of our screening process.

  • If you take part in a psychedelic-assisted psychotherapy trial you will be offered therapy and a psychedelic or a dummy drug. Therapy on its own can be helpful. Psychedelics have the potential to make therapy work better, but we don’t know for sure yet.

  • Researchers call the entry conditions for trials 'eligibility criteria'. Trials have these to make sure that the patients taking part in a trial are as similar as possible. That way, if one group does better than the other, researchers can be sure it was due to a difference in treatment and not due to their condition being more or less severe.

    Eligibility criteria are clearly written in trial protocols. Examples where there are clear guidelines around eligibility could be age or the types of medication you are on or the diagnosis that you have. Eligibility criteria change for all trials so while you may not be eligible for one trial you may be for another.

  • After you complete the short form, our clinical team reviews your details. If you’re a potential fit, we’ll invite you for a screening call and health check to confirm eligibility.

  • We run new studies throughout the year. Once you register, we’ll keep you updated when a suitable trial opens near you.

  • Our clinics are located in central London and Doncaster, with more sites launching soon.

  • We focus on neuro and psychiatric conditions.

    Psychiatry: Depression, PTSD, Anxiety Disorders, Eating Disorders, Substance Use Disorders, ADHD, and Autism Spectrum Disorder.

    Neurology: Pain, Migraine, Parkinson’s Disease, Alzheimer’s Disease, and Dementia.

  • Psychedelic drugs are a class of psychoactive substances that alter a person's perception, thoughts, and feelings. Examples of psychedelics include LSD, psilocybin (found in magic mushrooms), and DMT, which we study in our trials to treat conditions such as depression, post-traumatic stress disorder (PTSD) or adjustment disorder.

    Psychedelic clinical trials are research studies that investigate the safety and effectiveness of psychedelic substances as a treatment for various mental health conditions. These trials are conducted in a controlled, clinical setting under the guidance of trained healthcare professionals on either healthy volunteers or patients.

  • We do not focus on a specific drug and carry out clinical trials for any psychedelic drugs our clients are interested in studying. This includes psilocybin, LSD, MDMA, and 5-MeO-DMT among others.

  • All of our clinical trials are different so your involvement will vary depending on which trial you take part in. Some trials may involve multiple visits over a long period (in excess of 1 year) and on rare occasions may also require an overnight stay at one of our clinical facilities. You will be made fully aware of what taking part will involve before you decide to take part in any of our studies.

Articles on mental health, psychedelics and more. Read